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GH SecretagoguesTier 2 β€” Good human studies

GHRP-2

KP-102 Β· Pralmorelin

Potent GH secretagogue that also stimulates appetite via ghrelin receptors. Stronger GH release than Ipamorelin but with more cortisol and prolactin elevation.

πŸ’‰ SC injection🧊 Lyophilised: refrigerate; reconstituted: refrigerate, use within 30 days

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Mechanism of Action

Potent GHSR-1a agonist producing robust GH pulses. Also activates ghrelin signalling, increasing appetite and slightly elevating cortisol and prolactin.

Clinical Applications

  • βœ“Aggressive GH optimization
  • βœ“Appetite stimulation in wasting conditions
  • βœ“Post-workout recovery
  • βœ“Muscle mass building protocols

Dosing Protocol

Recommended Dosing

SC injection. 100–300 mcg, 1–3x daily, typically pre-workout and before bed. Use on empty stomach for maximum effect.

Safety & Contraindications

Possible Side Effects

  • ⚠Significant increase in appetite ("hunger peptide")
  • ⚠Cortisol and prolactin elevation
  • ⚠Water retention
  • ⚠Fatigue
  • ⚠Tingling/numbness

Contraindications

  • βœ•Active malignancy
  • βœ•Insulin resistance / diabetes (cortisol effect)
  • βœ•Prolactinoma
  • βœ•Pregnancy

Combinations & Synergies

πŸ”— CJC-1295potent GH stack for experienced users
πŸ”— Ipamorelincan substitute GHRP-2 for cleaner profile
#GH#appetite#muscle#recovery#cortisol
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