LongevityTier 3 β Animal + early human data
Epithalon
Epithalamin Β· Ala-Glu-Asp-Gly Β· Epitalon
Tetrapeptide derived from the pineal gland with telomerase-activating properties. Stimulates melatonin production and may slow cellular aging by elongating telomeres.
π SC injection / Intranasalπ§ Lyophilised: refrigerate or freeze; reconstituted: refrigerate, use within 30 days
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Mechanism of Action
Activates telomerase enzyme, potentially elongating telomeres in somatic cells. Also stimulates melatonin synthesis in the pineal gland and acts as an antioxidant.
Clinical Applications
- βLongevity and anti-aging protocols
- βSleep quality improvement (melatonin pathway)
- βCancer prevention (telomere stability theory)
- βImmune function in older adults
- βRetinal degeneration (emerging evidence)
Dosing Protocol
Recommended Dosing
SC injection or intranasal. 5β10 mg/day Γ 10β20 days per cycle, 1β2 cycles per year. Or 5 mg once daily for 5 days per month. Research compound β no standardised protocol.Safety & Contraindications
Possible Side Effects
- β Generally very well tolerated in studies
- β Injection site reactions
- β Unknown long-term safety
Contraindications
- βActive malignancy (telomerase activation theoretical concern)
- βPregnancy
Combinations & Synergies
π MOTS-ccomprehensive longevity stack
π Humanincombined anti-aging mitochondrial protocol
π Semaxcognitive longevity support