Metabolic Β· RegenerativeTier 3 β Animal + early human data
AOD-9604
Anti-Obesity Drug 9604 Β· hGH Fragment 176-191
Fragment of human GH (amino acids 176β191) that retains the lipolytic activity of GH without promoting growth or affecting blood sugar. Safe for diabetic patients.
π SC injectionπ§ Lyophilised: refrigerate; reconstituted: refrigerate, use within 30 days
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Mechanism of Action
Mimics GH's fat-burning action by stimulating beta-3 adrenergic receptors in adipose tissue and inhibiting lipogenesis, without activating IGF-1 or insulin signalling pathways.
Clinical Applications
- βTargeted fat loss without GH side effects
- βObesity management in insulin-resistant patients
- βComplementary to calorie restriction protocols
- βJoint regeneration (early evidence)
Dosing Protocol
Recommended Dosing
SC injection. 250β500 mcg once daily, typically in the morning on an empty stomach. Cycles of 12β16 weeks.Safety & Contraindications
Possible Side Effects
- β Generally well tolerated
- β Mild injection site reactions
- β Transient dizziness
Contraindications
- βPregnancy
- βActive malignancy
Combinations & Synergies
π Tesamorelincomplementary fat-reduction stack
π Semaglutidecan be used together for enhanced metabolic effect